A Curtailed Procedure for Selecting Among Treatments With Two Bernoulli Endpoints

نویسندگان

چکیده

This paper is concerned with a closed adaptive sequential procedure for selecting random-size subset containing experimental treatments that are better than standard. All the k under considerations measured by two endpoints accounting treatment efficacy and safety respectively. The selection made regard to binary endpoints. An considered be standard if its both have successful rates higher ones. We provide step-by-step sampling rule, stopping decision rule proposed procedure. show achieves same requirements probability of correct as does fixed-sample-size procedure, but requires fewer observations. use simulations evaluate sample size savings over corresponding

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ژورنال

عنوان ژورنال: Sankhya B

سال: 2021

ISSN: ['0976-8386', '0976-8394']

DOI: https://doi.org/10.1007/s13571-021-00261-2